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cell proliferation

ZMAT1 Acts as a Tumor Suppressor in Pancreatic Ductal Adenocarcinoma by Inducing SIRT3/p53 Signaling Pathway

[Journal of Experimental & Clinical Cancer Research] Multiple bioinformatics analyses were used to evaluate zinc finger matrin-type 1 (ZMAT1) expression and potential role in PDAC.In vitro and in vivo studies were performed to assess the effects of ZMAT1 on PDAC cells growth.

A Noncoding Regulatory RNA Gm31932 Induces Cell Cycle Arrest and Differentiation in Melanoma via the MiR-344d-3-5p/Prc1 (and Nuf2) Axis

[Cell Death & Disease] Integrative analysis of whole transcriptome sequencing data demonstrated that lncRNA-Gm31932 was significantly decreased in all-trans retinoic acid-induced and sodium 4-phenylbutanoate-induced mouse melanoma B16 cells.

CircLDLR Modulates the Proliferation and Apoptosis of Vascular Smooth Muscle Cells in Coronary Artery Disease through miR-26-5p/KDM6A Axis

[Journal of Cardiovascular Pharmacology] Researchers investigated the effect of circLDLR on the proliferation and apoptosis of vascular smooth muscle cells in coronary artery disease and its regulatory mechanism.

ZIC2 Promotes Colorectal Cancer Growth and Metastasis through the TGF-β Signaling Pathway

[Experimental Cell Research] The authors found that high ZIC2 expression was not only associated with poor prognosis, relapse-free survival and advanced metastasis but was also an independent prognostic factor in colorectal cancer patients.

Fraxetin Down-Regulates Polo-Like Kinase 4 (PLK4) to Inhibit Proliferation, Migration and Invasion of Prostate Cancer Cells through the Phosphatidylinositol 3-Kinase (PI3K)/Protein Kinase B (Akt)...

[Bioengineered] The prostatic epithelial cell RWPE-1 and prostate cancer cell DU145 were exposed to Fraxetin to detect the changes in cell viability using cell counting kit-8 assay.

PPFIA4 Promotes Castration-Resistant Prostate Cancer by Enhancing Mitochondrial Metabolism through MTHFD2

[Journal of Experimental & Clinical Cancer Research] Scientists investigated the expression of the protein tyrosine phosphatase receptor type F polypeptide interacting protein alpha 4 (PPFIA4) using public datasets and tumor specimens from prostate cancer cases by immunohistochemistry.

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