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cell proliferation

mRNP Granule Proteins Fmrp and Dcp1a Differentially Regulate mRNP Complexes to Contribute to Control of Muscle Stem Cell Quiescence and Activation

[Skeletal Muscle] Researchers investigated muscle tissue homeostasis in adult Fmr1-/- mice, analyzing myofiber cross-sectional area in vivo and satellite cell proliferation ex vivo, and explored the molecular mechanisms of Decapping protein 1a (Dcp1a) and Fragile X Mental Retardation Protein (Fmrp) function in quiescence, proliferation and differentiation.

NCK1-AS1 Promotes the Progression of Melanoma by Accelerating Cell Proliferation and Migration via Targeting miR-526b-5p/ADAM15 Axis

[Cancer Cell International] NCK1-antisense 1 (NCK1-AS1) was overexpressed in melanoma cell lines and NCK1-AS1 knockdown hampered the proliferation and migration of melanoma cells.

STAT3-Induced ZBED3-AS1 Promotes the Malignant Phenotypes of Melanoma Cells by Activating PI3K/AKT Signaling Pathway

[RNA Biology] Researchers discovered that ZBED3 antisense RNA 1 (ZBED3-AS1) was overexpressed in melanoma cells compared with human epidermal melanocytes.

Overexpression of PSMC2 Promotes the Tumorigenesis and Development of Human Breast Cancer via Regulating Plasminogen Activator Urokinase (PLAU)

[Cell Death & Disease] Loss-of-function study was used to evaluate the effects of Proteasome 26S subunit ATPase 2 (PSMC2) knockdown in cell proliferation, apoptosis and migration. Knockdown of PSMC2 suppressed breast cancer progression in vitro and in vivo.

MiR-223-3p Targets FOXO3a to Inhibit Radiosensitivity in Prostate Cancer by Activating Glycolysis

[Life Sciences] Researchers investigated the role of miR-223-3p in promoting radiotherapy resistance of prostate cancer cells by activating glycolysis.

Periostin Deficiency Reduces DEN-Induced Liver Cancer in Mice by Decreasing HSC Activation and Cancer Cell Proliferation

[Journal of Pathology] Scientists demonstrated that periostin was markedly upregulated in diethylnitrosamine (DEN)-induced mouse hepatocellular carcinoma tissues (HCC) and periostin knockout impaired DEN-induced HCC development.

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