Overexpression of PSMC2 Promotes the Tumorigenesis and Development of Human Breast Cancer via Regulating Plasminogen Activator Urokinase (PLAU)

Loss-of-function study was used to evaluate the effects of Proteasome 26S subunit ATPase 2 (PSMC2) knockdown in cell proliferation, apoptosis and migration. Knockdown of PSMC2 suppressed breast cancer progression in vitro and in vivo.