cell transplantation

[Current Stem Cell Research & Therapy] Investigators review the potential application of MSC extracellular vesicles as an emerging treatment strategy for optic neuritis by reviewing studies in multiple sclerosis and related disorders.

[Lancet Child & Adolescent Health] The authors provide a clinical decision support tool for pediatric hematologists, oncologists, and critical care physicians during the difficult decision-making process of extracorporeal membrane oxygenation candidacy and management.

[New England Journal of Medicine] In a Phase III clinical trial, scientists randomly assigned, in a 1:1 ratio, patients with large B cell lymphoma that was refractory to or had relapsed no more than 12 months after first-line chemoimmunotherapy to receive axicabtagene ciloleucel or standard care.

[Trends in Pharmacological Sciences] Beta cell replacement has emerged as an attractive therapeutic alternative to traditional exogenous insulin administration for management of type 1 diabetes.

[Artificial Organs] Investigators describe the decellularization and sterilization methods that are commonly used in recent research, and the effects of these methods upon biologic scaffold material.

[Leukemia & Lymphoma] Scientists discuss the limitations of currently approved treatment options and novel therapeutic targets with drug candidates in late-stage, Phase II or III, clinical development for the treatment of myelofibrosis.