cell transplantation

[Nature Reviews Rheumatology] Considerable advances have been made in predicting the extent and rate of skin-disease progression in diffuse cutaneous systemic sclerosis, including the development of techniques such as molecular analysis of skin biopsy samples.

[Journal of Clinical Immunology] Researchers studied transplant outcomes in severe combined immunodeficiency (SCID) infants according to donor type, specifically TCRαβ/CD19-depleted haploidentical family donor transplant, and conditioning, through retrospective cohort analysis of 52 consecutive infants with SCID transplanted between 2013 and 2020.

[Stem Cells Translational Medicine] Scientists discuss recent advances in understanding the mechanisms that regulate stem cell regeneration.

[Blood Advances] Recipients of hematopoietic stem cell transplantation showed weaker immune responses to COVID-19 vaccines than healthy controls

[Cancer Immunology Research] Researchers tested the in vitro effect of different natural killer (NK)-cell engagers, which triggered either NKp46 or NKp30 together with CD16A, and targeted either CD19 or CD20 to induce killing of pediatric B cell precursor acute lymphoblastic leukemia.

[Bone Marrow Transplantation] In 145 adult recipients developing chronic graft-versus-host disease (cGVHD) after matched sibling or umbilical cord blood donor hematopoietic cell transplantation from 2010 to 2018, two-year cumulative incidence of flares after cGVHD diagnosis was estimated at 60%, with median time-to-first flare of 188 days.