Tag results:
dendritic cells
Immunology of Infectious Disease News
Foxp3+ CD4+ Regulatory T Cells Control Dendritic Cells in Inducing Antigen-Specific Immunity to Emerging SARS-CoV-2 Antigens
[PLoS Pathogens] Investigators examined the effect of transient breakdown of the immunological tolerance induced by Treg-cell depletion on adaptive immune responses against administered SARS-CoV-2 antigen, spike protein 1.
Immunology of Infectious Disease News
Virus-Stimulated Dendritic Cells Elicit a T Antiviral Transcriptional Signature in Human CD4+ Lymphocytes
[Journal of Molecular Biology] Scientists identified a transcriptional signature associated with progressive resistance to HIV infection in CD4+ T cells.
Pulmonary Cell News
The Role of Immune Cells in Pulmonary Hypertension: Focusing on Macrophages
[Human Immunology] The authors reviewed the molecular mechanisms and the role of immune cells and responses involved in pulmonary hypertension development.
Immune Regulation News
Peripheral Tolerance by Treg via Constraining OX40 Signal in Autoreactive T Cells against Desmoglein 3, a Target Antigen in Pemphigus
[Proceedings of the National Academy of Sciences of the United States of America] Scientists used desmoglein 3, a pemphigus antigen expressed in keratinocytes, to analyze peripheral tolerance under physiological antigen-expression conditions.
Immune Regulation News
Meteorin-β/Meteorin Like/IL-41 Attenuates Airway Inflammation in House Dust Mite-Induced Allergic Asthma
[Cellular & Molecular Immunology] Increased Metrnβ effectively blocked the development of airway hyperreactivity and decreased inflammatory cell airway infiltration and type 2 cytokine production, which was associated with downregulated dendritic-mediated adaptive immune responses.
Immunology of Infectious Disease News
Engaging Innate Immunity in HIV-1 Cure Strategies
[Nature Reviews Immunology] Scientists discuss novel latency-reversing agents targeting DCs as well as DC-based strategies to enhance the clearance of infected cells by CD8+ T cells and strategies to improve the killing activity of natural killer cells.