Peripheral Tolerance by Treg via Constraining OX40 Signal in Autoreactive T Cells against Desmoglein 3, a Target Antigen in Pemphigus

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Scientists used desmoglein 3, a pemphigus antigen expressed in keratinocytes, to analyze peripheral tolerance under physiological antigen-expression conditions.
[Proceedings of the National Academy of Sciences of the United States of America]
Abstract