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endothelial cells

3D Spheroids of Human Placenta-Derived Mesenchymal Stem Cells Attenuate Spinal Cord Injury in Mice

[Cell Death & Disease] The authors found that 3D human placenta-derived MSCs demonstrated a significant increase in secretion of anti-inflammatory factors and trophic factors like VEGF, PDGF, FGF via QPCR and Bio-Plex assays.

Extracellular Vesicles Derived from Hypoxia-Preconditioned Olfactory Mucosa Mesenchymal Stem Cells Enhance Angiogenesis via miR-612

[Journal of Nanobiotechnology] Investigators explored the effects of extracellular vesicles from human hypoxic olfactory mucosa MSCs on angiogenesis and its underlying mechanism.

Three-Dimensional Printing of Bioceramic-Induced Macrophage Exosomes: Immunomodulation and Osteogenesis/Angiogenesis

[NPG Asia Materials] 3D printed macrophage exosomes scaffolds, exhibiting a predefined structure and persistent release of exosomes, displayed distinct immunomodulatory effects and improved osteogenesis/angiogenesis.

Developing a Pro-Angiogenic Placenta Derived Amniochorionic Scaffold with Two Exposed Basement Membranes as Substrates for Cultivating Endothelial Cells

[Scientific Reports] An optimized combination of enzymatic solutions with mechanical scrapping was used to remove the amniotic epithelium and chorion trophoblastic layer of a placenta membrane, which resulted in exposing the basement membranes of both sides without their separation and subsequent damages to the in-between spongy layer.

Mapping Protein Carboxymethylation Sites Provides Insights into Their Role in Proteostasis and Cell Proliferation

[Nature Communications] In primary endothelial cells, investigators showed that glyoxal induced cell cycle perturbation and that carboxymethyllysine modification reduced acetylation of tubulins and impaired microtubule dynamics.

Requirement of Direct Contact between Chondrocytes and Macrophages for the Maturation of Regenerative Cartilage

[Scientific Reports] Researchers examined the host cells that promoted cartilage maturation via cell–cell contact. Based on analysis of the transplanted chondrocytes, they examined the contribution of endothelial cells and macrophages.

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