epithelial cells

[Proceedings of the National Academy of Sciences of the United States of America] A strong response was induced in monocytes and B cells, with a SARS-CoV-2–specific inflammatory gene cluster distinct from that seen in influenza A or Ebola virus-infected cocultures, and which reproduced deviations reported in blood or lung myeloid cells from COVID-19 patients.

[Science Signaling] The authors reported that inhibitor of DNA binding protein 2 negatively regulated antiviral innate immune responses.

[Ebiomedicine] Bacterial factors related to the mucin2 (MUC2) mucus barrier play important roles in the response to changes in dietary patterns, MUC2 mucus barrier dysfunction, contact stimulation with colonic epithelial cells, and mucosal and submucosal inflammation during the occurrence and development of ulcerative colitis.

[Signal Transduction and Targeted Therapy] Scientists showed that SARS-CoV-2-triggered mast cells degranulation initiated alveolar epithelial inflammation and lung injury.

[Science of the Total Environment] Scientists revealed that reduced iron minerals were widely distributed within samples obtained from Australian coal mines with pyrite and siderite being particularly abundant. Compared with carbon and crystalline silica, the presence of these specific iron minerals were negatively correlated to the viability of both alveolar macrophages and human lung epithelial cells.

[Scientific Reports] In both clinical and histologic observations, epithelial cells were able to migrate and form multilayers over the polyethylene glycol-collagen hydrogels at the site of the corneal stromal defect.