[PLoS One] Investigators embedded a scaffold material containing conditioned medium of MSCs (MSC-CM) pretreated with IFN-γ and TNF-α and reconfirmed that cell migration and activation were superior to that in the presence of MSC-CM in vivo.
[Journal of Investigative Dermatology] Investigators confirmed that the rosacea-like skin inflammation induced by Cathelicidin LL37 was alleviated in aged mice and mice with progeria.
[Scientific Reports] Researchers elucidated the overall smoking-induced miRNA changes and those specific to chronic obstructive pulmonary disease (COPD).They investigated the downstream effects on regulatory gene expression and the correlation to cellular composition.
[Science Advances] Investigators undertook an integrative multiomics approach to delineate the process of induced myogenic progenitor cells reprogramming in comparison to myogenic transdifferentiation mediated solely by MyoD.
[Stem Cell Research] Scientists generated human induced pluripotent stem cells from fibroblasts of a 64-year-old male patient with a homozygous ILE368ASN mutation in PINK1, who experienced disease onset at 33 years.