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fibroblasts

The Conditioned Medium from Mesenchymal Stromal Cells Pretreated with Proinflammatory Cytokines Promote Fibroblasts Migration and Activation

[PLoS One] Investigators embedded a scaffold material containing conditioned medium of MSCs (MSC-CM) pretreated with IFN-γ and TNF-α and reconfirmed that cell migration and activation were superior to that in the presence of MSC-CM in vivo.

Aging-Conferred SIRT7 Decline Inhibits Rosacea-Like Skin Inflammation via Modulating TLR2-NF-κB Signaling

[Journal of Investigative Dermatology] Investigators confirmed that the rosacea-like skin inflammation induced by Cathelicidin LL37 was alleviated in aged mice and mice with progeria.

Rab13 Sustains Breast Cancer Stem Cells by Supporting Tumor-Stroma Crosstalk

[Cancer Research] Researchers reported that Rab13, a small GTPase, is highly expressed in breast CSCs.

High miR203a-3p and miR-375 Expression in the Airways of Smokers with and without COPD

[Scientific Reports] Researchers elucidated the overall smoking-induced miRNA changes and those specific to chronic obstructive pulmonary disease (COPD).They investigated the downstream effects on regulatory gene expression and the correlation to cellular composition.

Integrative Molecular Roadmap for Direct Conversion of Fibroblasts into Myocytes and Myogenic Progenitor Cells

[Science Advances] Investigators undertook an integrative multiomics approach to delineate the process of induced myogenic progenitor cells reprogramming in comparison to myogenic transdifferentiation mediated solely by MyoD.

Generation of Two Human Induced Pluripotent Stem Cell Lines from Fibroblasts of Parkinson’s Disease Patients Carrying the ILE368ASN Mutation in PINK1 (LCSBi002) and the...

[Stem Cell Research] Scientists generated human induced pluripotent stem cells from fibroblasts of a 64-year-old male patient with a homozygous ILE368ASN mutation in PINK1, who experienced disease onset at 33 years.

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