fibronectin

[Scientific Reports] Researchers investigated how ICG001 could prevent cardiac hypertrophy and fibrosis induced by transverse aortic constriction and found it may have mediated the substrates in the glycolysis pathway and the distinct alteration of oxidative stress during cardiac hypertrophy and heart failure.

[Scientific Reports] Molecular modeling methods were applied to build the inhibitory and non-inhibitory matrix metalloproteinase 9 (MMP-9)–TIMP-1 complexes, which allowed for a detailed description of these structures and allowed for a better understanding of the regulatory processes in which MMP-9 was involved.

[Scientific Reports] Researchers found that cells lacking the desmosomal cadherin Desmoglein-2 displayed a significant increase in spreading area on both fibronectin and collagen, compared to control A431 cells.

[Scientific Reports] The use of a xenogeneic-free medium provided a suitable alternative for human bone marrow MSC expansion, due the capability to maintain cell characteristic and potency.

[Clinical Cancer Research] A large cohort of chemotherapy-naïve triple-negative breast cancer (TNBC), clinicopathologic features, deconvoluted RNA immune signatures, and intraepithelial and stromal TIME were identified in subsets of PD-L1+ and PD-L1- TNBC.

[Scientific Reports] Scientists identified cell–cell and cell-ECM interactions in the microenvironment of the early four-chambered vertebrate heart that drive cardiomyocyte organization and alignment.