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flow cytometry

Detection of the HIV-1 Accessory Proteins Nef and Vpu by Flow Cytometry Represents a New Tool to Study Their Functional Interplay within a Single...

[Journal of Virology] Researchers showed that the combined expression of Nef and Vpu predicted the susceptibility of HIV-1-infected primary CD4+ T cells to antibody-dependent cellular cytotoxicity by HIV+ plasma.

CDK12 Activates MYC to Repress miR-28-5p/EZH2 and Amplifies Tonic BCR Signaling to Promote the Development of Diffuse Large B Cell Lymphoma

[Cancer Gene Therapy] Cyclin-dependent kinase 12 (CDK12) activated MYC to repress miR-28-5p/EZH2 and amplified tonic BCR signaling to promote the development of diffuse large B cell lymphoma (DLBCL), which might provide potential therapeutic targets for future therapeutic intervention in DLBCL.

Endoplasmic Reticulum Stress Promotes Breast Cancer Cells to Release Exosomes circ_0001142 and Induces M2 Polarization of Macrophages to Regulate Tumor Progression

[Pharmacological Research] Scientists screened and verified the differential expression of circ_0001142 in breast cancer tissues and cell lines through bioinformatics and qRT-PCR.

Increased Expression of PD-L1 in Endometrial Cancer Stem-Like Cells Is Regulated by Hypoxia

[Frontiers in Bioscience-Landmark] Using flow cytometry and western blot assays, the authors have demonstrated that programmed cell death ligand 1 expression is higher in endometrial cancer stem-like cell derived from endometrial cancer than in nonstem-like cancer cells.

MSC-Derived Extracellular Vesicle-Delivered L-PGDS Inhibit Gastric Cancer Progression by Suppressing Cancer Cell Stemness and STAT3 Phosphorylation

[Stem Cells International] Researchers explored whether Mesenchymal stem cell- (MSC-) derived extracellular vesicles-delivered lipocalin-type prostaglandin D2 synthase (L-PGDS) could inhibit gastric cancer progression.

CircCHMP5 Contributes to Ox-LDL-Induced Endothelial Cell Injury through the Regulation of MiR-532-5p/ROCK2 Axis

[Cardiovascular Drugs and Therapy] Oxidized low-density lipoprotein was used to treat human umbilical vein endothelial cells to construct a cell injury model. The expression level of circCHMP5, miR-532-5p, and Rho-associated protein kinase 2 was measured using quantitative real-time PCR.

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