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flow cytometry
Cell Therapy News
Combine and Conquer: Manganese Synergizing Anti-TGF-β/PD-L1 Bispecific Antibody YM101 to Overcome Immunotherapy Resistance in Non-Inflamed Cancers
[Journal of Hematology & Oncology] The synergistic effect between Bivalent manganese and YM101 in vitro was determined by one-way mixed lymphocyte reaction, CFSE dilution assay, and cytokine detection.
Cell Therapy News
Mesenchymal Stem Cells Act as Stimulators of Neurogenesis and Synaptic Function in a Rat Model of Alzheimer’s Disease
[Heliyon] The possible roles of human umbilical mesenchymal stromal cord and adipose mesenchymal stem cells in neurogenesis and synaptic function were investigated using a β-amyloid 1-42-induced Alzheimer's disease rat model.
Dermal Cell News
lncRNA TINCR Attenuates the Proliferation and Invasion, and Enhances the Apoptosis of Cutaneous Malignant Melanoma Cells by Regulating the miR-424-5p/LATS1 Axis
[Oncology Reports] Researchers evaluated the role of the lncRNA TINCR ubiquitin domain containing TINCR in cutaneous malignant melanoma in vitro and in vivo.
Hepatic Cell News
The RNA Binding Protein HuR Is a Gatekeeper of Liver Homeostasis
[Hepatology] On a non-alcoholic fatty liver disease-inducing diet, hepatocyte-specific HuR-deficiency resulted in exacerbated inflammation, fibrosis and hepatocellular carcinoma -like tumor development. A multi-omic approach revealed that HuR orchestrated a protective network of hepatic-metabolic and lipid homeostasis-maintaining pathways.
Prostate Cell News
eIF5B Regulates the Expression of PD-L1 in Prostate Cancer Cells by Interacting with Wig1
[BMC Cancer] The effects of interference with eIF5B expression on the growth, morphology, and immunity of the tumor, as well as PD-L1 expression in the tumor, were verified by tumor xenograft assays in vivo.
Pulmonary Cell News
Identification of circ_0058357 as a Regulator in Non-small Cell Lung Cancer Cells Resistant to Cisplatin by miR-361-3p/ABCC1 Axis
[Thoracic Cancer] Researchers identified the precise role of circular RNA circ_0058357 in the functional properties of DDP-resistant non-small cell lung cancer cells.