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flow cytometry

Efficacy of Venetoclax plus Rituximab for Relapsed CLL: 5-Year Follow-Up of Continuous or Limited- Duration Therapy

[Blood] The authors reported long-term follow-up of the Phase Ib study of venetoclax and rituximab in patients with relapsed chronic lymphocytic leukemia (CLL), including outcomes with continuous or limited-duration therapy.

Extracellular Vesicles Derived from CD73 Modified Human Umbilical Cord Mesenchymal Stem Cells Ameliorate Inflammation after Spinal Cord Injury

[Journal of Nanobiotechnology] Effects of CD73+ human umbilical cord MSC-EVs on hydrolyzing ATP into adenosine were detected. The polarization of M2/M1 was verified by immunofluorescence.

Extracellular Vesicles Derived from CD73 Modified Human Umbilical Cord Mesenchymal Stem Cells Ameliorate Inflammation after Spinal Cord Injury

[Journal of Nanobiotechnology] Scientists constructed CD73 modified extracellular vesicles and explored the anti-inflammatory effects after spinal cord injury. CD73 engineered extracellular vesicles were derived from human umbilical cord MSCs transduced by lentiviral vectors to upregulate the expression of CD73.

Early Activation of the Cardiac CX3CL1/CX3CR1 Axis Delays β-Adrenergic-Induced Heart Failure

[Scientific Reports] Investigators characterized macrophages in hearts early infused with isoproterenol as compared to control and failing hearts and evaluated the role of upregulated CX3CL1 in cardiac remodeling.

RecQ-Like Helicase 4 (RECQL4) Exacerbates Resistance to Oxaliplatin in Colon Adenocarcinoma via Activation of the PI3K/AKT Signaling Pathway

[Bioengineered] Researchers found RECQL4 was upregulated in colon adenocarcinoma (COAD), especially in Oxaliplatin-resistant COAD tissues and cells.

CML Derived Exosomes Promote Tumor Favorable Functional Performance in T Cells

[BMC Cancer] Human primary cord blood-derived T cells were treated with K562-derived exosomes. Scientists evaluated the expression variation of some critical genes activated in suppressor T cells.

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