Tag results:
granulocytes
Human Immunology News
Eosinophil Extracellular Traps Drive Asthma Progression through Neuro-Immune Signals
[Nature Cell Biology] Scientists showed that eosinophil extracellular traps in bronchoalveolar lavage fluid are associated with the severity of asthma in patients.
Pulmonary Cell News
Cis-Acting Lnc-Cxcl2 Restrains Neutrophil-Mediated Lung Inflammation by Inhibiting Epithelial Cell CXCL2 Expression in Virus Infection
[Proceedings of the National Academy of Sciences of the United States of America] Scientists identified an inducible lncRNA in the Cxcl2 gene locus, lnc-Cxcl2, which could selectively inhibit Cxcl2 expression in mouse lung epithelial cells but not in macrophages.
Cell Therapy News
ATG and Post-Transplant Cyclophosphamide Predisposes to Inferior Outcome When Using Cryopreserved Stem Cell Grafts
[European Journal of Haematology] Scientists analyzed the outcomes of 483 patients who received hematopoietic stem cell transplantation between August 2017 and August 2020 in a retrospective study, comparing the outcomes between those who received cryopreserved or fresh peripheral blood stem cell grafts.
Human Immunology News
Soluble PD-L1 Is a Predictive and Prognostic Biomarker in Advanced Cancer Patients Who Receive Immune Checkpoint Blockade Treatment
[Scientific Reports] Researchers investigated the significance of sPD-L1 in cancer patients receiving immune checkpoint inhibitor therapy.
Human Immunology News
CD177 Modulates the Function and Homeostasis of Tumor-Infiltrating Regulatory T Cells
[Nature Communications] Using single-cell RNA sequencing of immune cells from renal clear cell carcinoma patients, investigators identified two distinct transcriptional fates for tumor-infiltrating Treg cells, Fate-1 and Fate-2.
Immune Regulation News
Understanding Human Mast Cells: Lesson from Therapies for Allergic and Non-Allergic Diseases
[Nature Reviews Immunology] Scientists discuss the existing and emerging therapies that target mast cells, and they consider how these treatments can help us to understand mast cell functions in disease.