granulocytes

[Stem Cell Research & Therapy] MSCs were comparable to N-acetylcysteine against acetaminophen (APAP)-induced liver failure by secreting hepatocyte growth factor with less regenerative retardation concerns, thus facilitating the application of MSCs in clinical therapy for APAP liver failure.

[Proceedings of the National Academy of Sciences of the United States of America] Researchers found that TLR4 signaling in vascular endothelial cells and downstream NADPH oxidase 4 expression mediate the arrest of neutrophils, a step upstream of their extravasation.

[Cell Death & Disease] The authors performed flow cytometry and single-cell RNA sequencing to examine the immune cell landscape of excisional wounds from Angptl4+/+ and Angptl4−/− mice.

[Clinical and Translational Medicine] Ten fresh human tissue samples from six patients, including primary tumor and adjacent non-tumoral samples and six metastases from different organs or tissues were evaluated using single-cell RNA sequencing.

[Nature Communications] Researchers demonstrated that Lin28B promoted lung metastasis of breast cancer by building an immune-suppressive pre-metastatic niche.

[Journal of Leukocyte Biology] Researchers hypothesized that cystic fibrosis airway neutrophils contributed to chronic inflammation, in part, via the packaging of inflammasome-inducing signals in extracellular vesicles.