insulin

[Scientific Reports] The authors revealed the important role of insulin gene enhancer-binding protein 1 (ISL1) in androgen receptor (AR)-dependent prostate cancer cell growth; ISL1 knockdown reduced the AR activity and cell growth.

[Sanofi and Roche Diabetes Care France (GlobeNewswire, Inc.)] Sanofi and Roche Diabetes Care France have joined forces regarding the smart device Mallya® for SoloStar developed by Biocorp specializing in the development and manufacture of medical devices and injectable drug delivery systems.

[Biochimie] Semaglutide increased islet cell proliferation and recovered islet size and alpha- and beta-cell masses.

[Biochemical Pharmacology] Scientists discuss the implications of a heterogenous insulin secretory granules (ISG) population in β-cells and highlight the need for more understanding into how unique ISG populations may be targeted in anti-diabetic therapies.

[Journal of Diabetes Research] Scientists review recent study updates of sphingosine 1 phosphate (S1P), summarizing its effects on type 2 diabetes mellitus with respect to pathogenesis, promoting β cell proliferation and inhibiting apoptosis, reducing insulin resistance, protecting the liver and pancreas from lipotoxic damage, improving intestinal incretin effects, lowering basal glucagon levels, etc.

[PLoS One] A new “endocrine pancreas” delivered islet hormones physiologically into the hepatic portal vein. Treatment of insulin-dependent dogs with allogeneic canine Neo-Islets consistently improved glycemic control without the need for antirejection drugs.