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intestinal cells

Camel Whey Protein Hydrolysates Induced G2/M Cellcycle Arrest in Human Colorectal Carcinoma

[Scientific Reports] Peptides from milk proteins is gaining popularity in various therapeutics including human cancer. Researchers investigated the anti-cancerous and anti-inflammatory properties of camel whey protein hydrolysates

Suppression of Elevated Cdc42 Activity Promotes the Regenerative Potential of Aged Intestinal Stem Cells

[iScience] Elevation of Cdc42 activity in young animals by genetic means causes premature ISC aging, whereas pharmacological suppression of elevated Cdc42 activity restores organoid formation potential in vitro.

Porcine Colonoids and Enteroids Keep the Memory of Their Origin during Regeneration

[American Journal of Physiology-Cell Physiology] Colonoid and enteroid gene expression signatures were more similar to those found for the tissues of their origin than to each other.

The Murine Intestinal Stem Cells Are Highly Sensitive to the Modulation of the T3/TRα1-Dependent Pathway

[Development] By using ex vivo 3D organoid cultures and molecular approaches scientists observed early responses to T3 involving the T3-metabolizing enzyme Dio1 and the transporter Mct10, accompanied by a complex response of stem cell- and progenitor-enriched genes.

Restitution of Epithelial Cells during Intestinal Mucosal Wound Healing: The Effect of a Polysaccharide from the Sclerotium of Lignosus rhinocerotis (Cooke) Ryvarden

[Journal of Ethnopharmacology] Researchers investigated the effect and mechanism of β-glucan prepared from Lignosus rhinocerotis using an enzymatic method on epithelial restitution during intestinal mucosal damage.

Differential Protection by Anthocyanin-Rich Bilberry Extract and Resveratrol against Lipid Micelle-Induced Oxidative Stress and Monolayer Permeability in Caco-2 Intestinal Epithelial Cells

[Food & Function] In a Caco-2 cell model of dietary fat-induced intestinal epithelial cell cytotoxicity, oxidative stress and barrier impairment, researchers investigated the relative protection afforded by an anthocyanin-rich bilberry extract or resveratrol.

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