Suppression of Elevated Cdc42 Activity Promotes the Regenerative Potential of Aged Intestinal Stem Cells

By
Justin.choi
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0
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Elevation of Cdc42 activity in young animals by genetic means causes premature ISC aging, whereas pharmacological suppression of elevated Cdc42 activity restores organoid formation potential in vitro.
[iScience]
Nalapareddy, K., Hassan, A., Sampson, L., Zheng, Y., & Geiger, H. (2021). Suppression of elevated Cdc42 activity promotes the regenerative potential of aged intestinal stem cells. IScience, 0(0). https://doi.org/10.1016/j.isci.2021.102362 Cite
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