intestinal cells

[Nature Communications] Scientists showed that smooth muscle cells might be the dominant suppliers of BMP antagonists, which are niche factors essential for intestinal stem cell maintenance.

[Nature Materials] Investigators reported a family of synthetic hydrogels that promoted extensive organoid morphogenesis through dynamic rearrangements mediated by reversible hydrogen bonding.

[Genome Medicine] Investigators identified 145 genes from IBD-associated genomic loci having endogenous expression within the intestinal epithelial cell compartment.

[American Journal of Physiology-Gastrointestinal and Liver Physiology] Scientists showed that IL22 treatment induced the phosphorylation of STAT3, inhibited colonic organoid growth, and promoted colonic cell proliferation in vivo.

[Cell Reports] Mice with an intestinal epithelial cells-intrinsic deletion of MHC class II were healthy but have fewer microbial-bound IgA, regulatory T cells, and immune repertoire selection.

[Cell Stem Cell] Scientists defined the regulation of enteric glial cells heterogeneity in homeostasis and chronic inflammatory bowel disease.