intestinal epithelial cells

[Bioengineered] Researchers clarified the role of hydroxysafflor yellow A in inhibiting colorectal cancer in vitro and the underlying mechanisms.

[Frontiers in Immunology] Scientists summarize the changes brought about by the changes of commensal bacteria to the inflammation of the intestines and their mutual influence.

[Cell Metabolism] Scientists examined the microbial regulation of hexokinase 2 and its impact on inflammation using mice lacking hexokinase 2 in intestinal epithelial cells.

[Genome Medicine] Investigators identified 145 genes from IBD-associated genomic loci having endogenous expression within the intestinal epithelial cell compartment.

[Cell Reports] Mice with an intestinal epithelial cells-intrinsic deletion of MHC class II were healthy but have fewer microbial-bound IgA, regulatory T cells, and immune repertoire selection.

[Mucosal Immunology] A combination of genetic and genomic approaches were used to define a critical role of IEC-intrinsic negative elongation factor (NELF) complex in maintenance of epithelial homeostasis.