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keratinocytes

Activation of Matrix Metalloproteinases and FoxO3a in HaCaT Keratinocytes by Radiofrequency Electromagnetic Field Exposure

[Scientific Reports] The authors evaluated the use and trends of active comparator trial designs in dermatology.

Female Immunity Protects from Cutaneous Squamous Cell Carcinoma

[Clinical Cancer Research] Researchers presented data showing women presented less aggressive primary cutaneous squamous cell carcinoma and early strong immune activation.

Bacteria Induce Skin Regeneration via IL-1β Signaling

[Cell Host & Microbe] The Scientists assessed the function of skin bacteria in wound healing and wound-induced hair follicle neogenesis (WIHN), a rare adult organogenesis model.

Human Skin Aging is Associated with Increased Expression of the Histone Variant H2A.J in the Epidermis

[npj Aging and Mechanisms of Disease] The Scientists investigated histone variant H2A.J as a new biomarker to detect senescent cells during human skin aging.

In Vitro Skin Culture Media Influence the Viability and Inflammatory Response of Primary Macrophages

[Scientific Reports] Scientists showed that skin maturation was affected by culture in macrophage medium, while macrophages showed reduced viability, altered cell morphology and decreased response to pro- and anti-inflammatory stimuli in skin differentiation media, both in 2D and 3D.

Interaction of the NRF2 and p63 Transcription Factors Promotes Keratinocyte Proliferation in the Epidermis

[Nucleic Acids Research] The authors discovered an unexpected interaction between the cytoprotective transcription factor NRF2 and p63- a key player in epithelial morphogenesis.

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