leukocytes

[Gene] After incubation of the HUVECs with HA of H1N1 for 24 hours, the mRNA and protein of ICAM-1 and IL-6 in HUVECs were increased in group of 5μg/ml concentration with statistical significance.

[Cell Biology and Toxicology] Scientists examined the effects and mechanisms of action of vitamin D3 on the expression of intercellular adhesion molecule-1 in vitro and in vivo with or without tumor necrosis factor α treatment.

[Stem Cell Research & Therapy] Umbilical cord (UC)-MSCs have few human leukocyte antigen-II and major histocompatibility complex class I molecules, and are easy to isolate and culture, UC-MSC sheets have been proposed as a candidate for clinical applications to ischemic heart disease.

[International Cytokine and Interferon Society] Congratulations to Dr. Douglas Philip Dyer! Dr Dyer undertook his PhD research investigating how an anti-inflammatory protein functions by disrupting the interactions between chemokines and their ECM glycosaminoglycan binding partners. Supervised by Prof. Anthony Day, Dr Caroline Milner and Dr Amanda Proudfoot.

[Nature Cancer] Scientists quantified peptide repertoire breadth of a representative set of HLA-I alleles and found that patients with cancer who were carrying HLA-I alleles with high peptide-binding promiscuity have significantly worse prognosis after immune checkpoint inhibition.

[Molecular Genetics and Metabolism Reports] Researchers performed a cord blood hematopoietic cell transplantation with a reduced intensity conditioning on a nine-year-boy with adrenoleukodystrophy.