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leukocytes

Clinical Characterization and Immunosuppressive Regulation of CD161 (KLRB1) in Glioma through 916 Samples

[Cancer Science] Retrospective RNA-seq data analysis was conducted in a cohort of 313 patients with glioma in the Chinese Glioma Genome Atlas database and 603 patients in the TCGA database.

CRISPR/Cas9-Engineered HLA-Deleted Glomerular Endothelial Cells as a Tool to Predict Pathogenic Non-HLA Antibodies in Kidney Transplant Recipients

[Journal of the American Society of Nephrology] The authors designed a non-human leukocyte antigen (HLA) antibody detection immunoassay using HLA class I and II–deficient glomerular endothelial cells that had been previously generated through CRISPR/Cas9-induced B2M and CIITA gene disruption.

Sequential Modulation of the Wnt/β-Catenin Signaling Pathway Enhances Tumor-Intrinsic MHC I Expression and Tumor Clearance

[Gynecological Oncology] Human tumor samples and in vivo patient-derived xenograft and syngeneic murine models were administered Wnt/β-catenin modulating agents DKN-01 and CGX-1321 individually or in sequence

Mechanisms of Viral Inflammation and Disease in Humans

[Science] Single-gene inborn errors of cell-intrinsic or leukocytic immunity underlying diverse infections in the skin, brain, or lungs can help to clarify the human determinants of viral disease.

Comparing Cord Blood Transplantation and Matched Related Donor Transplantation in Non-remission Acute Myeloid Leukemia

[Leukemia] Researchers investigated the impact of cord blood transplantation, compared to human leukocyte antigen-matched related donor transplantation.

Comparing Cord Blood Transplantation and Matched Related Donor Transplantation in Non-Remission Acute Myeloid Leukemia

[Leukemia] Scientists investigated the impact of cord blood transplantation, compared to human leukocyte antigen-matched related donor transplantation.

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