lung carcinoma

[Scientific Reports] Scientists established siRNA-transfected small-cell lung carcinoma cell lines to investigate the anticancer effect of silencing ribonucleotide reductase large subunit gene expression.

[Journal of Cellular and Molecular Medicine] Since angiotensin-converting enzyme 2 (ACE2)-positive cells were hosts for COVID-19, researchers focussed on this cell type to explore the underlying mechanisms of COVID-19.

[Nature] Researchers identified distinct populations of macrophages that were enriched in human and mouse lung tumors.

[Nature Communications] Scientists showed that mice with genetic knockout of Ppm1d or with conditional knockout of Ppm1d in the hematopoietic system, in myeloid cells, or in neutrophils all displayed significantly reduced growth of syngeneic melanoma or lung carcinoma tumors.

[Scientific Reports] Reserachers investigated the effects of hyperbaric oxygen treatment (HBOT) on solid tumors, such as lung cancer. Non-small cell human lung carcinoma A549-cell-transferred severe combined immunodeficiency mice were selected as an in vivo model to detect the potential mechanism of HBOT in lung tumors.

[Scientific Reports] The authors applied the pipeline to a breast cancer model, and found that the L1PA2 transposon subfamily contributes abundant regulatory sequences to co-ordinated transcriptional regulation in breast cancer.