Tissue-Resident Macrophages Provide a Pro-Tumorigenic Niche to Early NSCLC Cells

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Researchers identified distinct populations of macrophages that were enriched in human and mouse lung tumors.
[Nature]
Casanova-Acebes, M., Dalla, E., Leader, A. M., LeBerichel, J., Nikolic, J., Morales, B. M., Brown, M., Chang, C., Troncoso, L., Chen, S. T., Sastre-Perona, A., Park, M. D., Tabachnikova, A., Dhainaut, M., Hamon, P., Maier, B., Sawai, C. M., Agulló-Pascual, E., Schober, M., … Merad, M. (2021). Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells. Nature, 1–7. https://doi.org/10.1038/s41586-021-03651-8 Cite
Abstract