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lupus

Importance of Lymphocyte–Stromal Cell Interactions in Autoimmune and Inflammatory Rheumatic Diseases

[Nature Reviews Rheumatology] The authors describe the importance of lymphocyte-stromal cell interactions in chronic inflammation, with a focus on human disease, using three selected autoimmune and inflammatory diseases.

Lupus Foundation of America Provides Six Grants to Young Scientists Supporting Important Lupus Research

[The Lupus Foundation of America] The Lupus Foundation of America announced six recipients of the 2021 Gina M. Finzi Memorial Student Summer Fellowship Program. The fellowship program provides grant and mentorship support for young scientists and plays an important role in establishing the next generation of lupus researchers and the future of the lupus research field.

Mesenchymal Stem Cells: Ideal Seeds for Treating Diseases

[Human Cell] MSCs, a kind of multipotent stem cells with self-renewal ability and multi-differentiation ability, have become the “practical stem cells” for the treatment of diseases.

New NIH Research Initiative Supported by LFA Focuses on the Causes of Inflammation and Clinical Disease

[The Lupus Foundation of America] The Lupus Foundation of America has renewed its support for the National Institutes of Health (NIH) Accelerating Medicines Partnership (AMP) which recently announced a new initiative to discover the causes of inflammation and clinical disease. The new AMP Autoimmune and Immune-Mediated Diseases (AMP AIM) Program will use novel analytics to examine the interaction among innate and adaptive immune cells and tissue-resident cells.

Splicing Factor SRSF1 Is Indispensable for Regulatory T Cell Homeostasis and Function

[Cell Reports] Researchers showed that serine/arginine-rich splicing factor 1, which was decreased in T cells from patients with systemic lupus erythematosus, was necessary for the homeostasis and proper function of Treg cells.

The Severity of Glomerular Endothelial Cell Injury Is Associated with Infiltrating Macrophage Heterogeneity in Endocapillary Proliferative Glomerulonephritis

[Scientific Reports] The authors examined 42 renal biopsy samples representing endocapillary proliferative lesions from post-streptococcal acute glomerulonephritis, Henoch–Schönlein purpura nephritis, and lupus nephritis

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