lymphocytes

[Advances in Therapy] The authors analyze and discuss the novel therapies for advanced basal cell carcinoma and squamous cell carcinoma to obtain a sharper perspective of the available treatment options.

[Oncogene] Researchers investigated the role of the NFE2L3 transcription factor in inflammation-induced colorectal cancer.

[Cell Death Discovery] Utilizing an integrated strategy based on scRNA-seq, scTCR-seq, and bulk RNA-seq analysis of fibrotic hypersensitivity pneumonitis profiles, the authors identified ten major cell types and 19 unique subtypes.

[Aging] Investigators indicated that TEAD2/4 were significantly upregulated in HCC compared with normal tissues. Downregulation of TEAD2 promoted the death of HCC cells through inducing ferroptosis by iron accumulation and subsequent oxidative damage.

[Journal of Experimental Medicine] The authors showed that toll/interleukin-1 receptor domain containing adaptor protein (TIRAP) was overexpressed in various types of myelodysplastic syndromes and suppressed all three major hematopoietic lineages.

[Expert Reviews in Molecular Medicine] With several hundred clinical trials undergoing worldwide, the pace that CAR-T immunotherapy moves from bench to bedside is unprecedented.