lymphoid cells

[Cancer Research] Investigators described a chemotherapy-induced, host-mediated mechanism that promoted remodeling of the ECM, ultimately facilitating cancer cell seeding and metastasis.

[Nature Communications] Scientists developed a strategy to compare the epigenetic and transcriptional make-up of primary glioblastoma cells with patient-matched expanded potential stem cell (EPSC)-derived neural stem cells.

[International Immunology] To apply the iPSC-based cell therapy in an allogeneic setting, the authors developed a method in which non-T cell-derived iPSCs were transduced with exogenous T cell receptor genes.

[Journal of Cancer] Investigators evaluated programmed cell death ligand-1 (PD-L1) expression in colorectal CSCs (CCSCs) and non-CCSCs and designed a combination immunotherapy synchronously utilizing PD-L1-CAR-T cells together with CCSC-dendritic cells vaccine-sensitized T cells for the treatment of colorectal cancer.

[Critical Reviews in Oncology/Hematology] Investigators introduce the mechanism of platelet-related tumor metastasis and particularly focus on the role of cell adhesion molecules in it.

[Proceedings of the National Academy of Sciences of the United States of America] Scientists comprehensively examined preproinsulin specificity of CD8 T cells obtained from pancreatic islets of organ donors with and without type 1 diabetes (T1D) and identified epitopes throughout the entire preproinsulin protein and defective ribosomal products derived from preproinsulin messenger RNA.