lymphoid cells

[Blood] The authors revealed a frequent activation of RelB in a large cohort of diffuse large B-cell lymphoma patients and cell lines, independently of their ABC or GCB subtypes.

[Science Translational Medicine] Researchers observed that tumor cell intrinsic loss of A20 markedly enhanced lung tumorigenesis and was associated with reduced CD8+ T cell–mediated immune surveillance in patients with lung cancer and in mouse models.

[Science Translational Medicine] To specifically trigger sufficient antitumor reactivity without notable adverse effects, scientists developed an antigen and adjuvant codelivery nanoparticle vaccine based on Escherichia coli cytoplasmic membranes (EMs) and tumor cell membranes (TMs) from resected autologous tumor tissue.

[Nature Biomedical Engineering] Scientists reported injectable biomaterial vaccines that triggered potent humoral and T-cell responses to bacterial antigens by recruiting, reprogramming and releasing dendritic cells.

[Proceedings of the National Academy of Sciences of the United States of America] Researchers reported that ventrolateral medulla (VLM) catecholaminergic neurons in the mouse brain were activated in tumor-bearing mice and the activity of these neurons significantly altered tumor growth in multiple syngeneic and spontaneous mouse tumor models.

[Cell Death Discovery] Scientists explored the role of exosomes derived from palmitic acid -treated hepatocytes in regulating hepatic stellate cells (LX-2 cell) proliferation and activation and the underlying mechanisms.