lymphoid cells

[Frontiers in Immunology] The authors provide an overview of the major mechanisms used by tumor cells to evade immune defenses and they critically expose the most optimistic engineering strategies to make CAR-T cell therapy a solid option for solid tumors.

[Biophysical Journal] The authors demonstrated that T cells exposed to high-e dose-dependently accumulated [K+]e intracellularly.

[Immunity] Researchers examined the impact of aryl hydrocarbon receptor in tumor-associated macrophage function in pancreatic ductal adenocarcinoma.

[Frontiers in Immunology] The frequencies of IFN-gamma producing pp38 and MEQ-specific T cell responses were determined in line N and line P2a chickens after infection with vaccine and/or virulent strains of Marek’s disease virus using both standard ex vivo and cultured chIFN-gamma ELISPOT assays.

[Nature Immunology] Interruption of T cell antigen receptors-mediated ‘normality sensing’ had no impact on γδ T cell numbers but altered their signature phenotype, while the epidermal barrier function was compromised.

[Molecular Biology Reports] Researchers assessed the suppressing effect of VGB4, a vascular endothelial growth factor (VEGF) antagonist peptide with the binding ability to both VEGF receptor1 and VEGF receptor2, on VEGF-induced proliferation and migration of the human lung adenocarcinoma cell line A549 and the human colon adenocarcinoma cell line HT29.