lymphoid cells

[Cell Death Discovery] Utilizing an integrated strategy based on scRNA-seq, scTCR-seq, and bulk RNA-seq analysis of fibrotic hypersensitivity pneumonitis profiles, the authors identified ten major cell types and 19 unique subtypes.

[Aging] Investigators indicated that TEAD2/4 were significantly upregulated in HCC compared with normal tissues. Downregulation of TEAD2 promoted the death of HCC cells through inducing ferroptosis by iron accumulation and subsequent oxidative damage.

[Journal of Experimental Medicine] The authors showed that toll/interleukin-1 receptor domain containing adaptor protein (TIRAP) was overexpressed in various types of myelodysplastic syndromes and suppressed all three major hematopoietic lineages.

[Expert Reviews in Molecular Medicine] With several hundred clinical trials undergoing worldwide, the pace that CAR-T immunotherapy moves from bench to bedside is unprecedented.

[INmune Bio, Inc.] INmune Bio, Inc. announced that the company has entered into a pre-clinical research collaboration with Chinese University of Hong Kong to evaluate INKmune™ in nasopharyngeal cancer, a type of head and neck cancer.

[Science Immunology] Scientists characterized tissue-resident memory B cells that were stably maintained in the lungs of mice after pulmonary influenza infection.