lymphoid cells

[Biomedicine & Pharmacotherapy] The development of biomarkers is important for monitoring the effect of treatment, assessing the patient's response to immune checkpoint inhibitors, determining adverse reactions, and predicting the direction of disease development.

[Scandinavian Journal of Immunology] The authors analyzed the influence of its precursor 25-hydroxyvitamin D3 on the differentiation of human CD4+ T cells applying physiological concentrations in vitro.

[Nature Reviews Nephrology] The understanding of T cell memory responses changed drastically with the discovery that specialized T cell memory populations reside within peripheral tissues at key pathogen entry sites.

[Cell Reports] The authors observed distinct locations for parasite-specific T cell subsets, implying a link between differentiation and anatomical niches in the spleen.

[Microbiome] Scientists investigated the regulatory effects of the gut microbiota on IL-35+ cells by using genetically modified mouse models of obesity.

[Lyell Immunopharma, Inc.] Lyell Immunopharma, Inc. announced that the US FDA has cleared an Investigational New Drug (IND) application to initiate a Phase I clinical trial for LYL132, an investigational T-cell receptor therapy for patients with solid tumors expressing New York esophageal squamous cell carcinoma 1 that the company is developing in collaboration with GSK.