lymphoma

[Seminars in Cancer Biology] The authors review the advancements in transformed SCLC, including clinical and pathological characteristics, and the potential effective treatment after SCLC transformation, aiming to give a better understanding of transformed SCLC and provide support for clinical uses.

[Journal of Photochemistry and Photobiology B-Biology] Researchers found that blue light-induced oxidative stress triggered the endoplasmic reticulum stress-C/EBP homologous protein signal and affected the protein levels of B-cell lymphoma-2 (Bcl-2) and Bcl2-associated X, thereby promoting apoptosis.

[Nature Medicine] Researchers investigated the role of the intestinal microbiome onvarious outcomes in a multicenter study of patients with B cell lymphoma and leukemia.

[Basic Research in Cardiology] Researchers established an in vitro iPSC model of anthracycline-induced cardiotoxicity (ACT) from patients with an aggressive form of B-cell lymphoma and examined whether doxorubicin-treated ACT-iPSC cardiomyocytes could recapitulate the clinical features exhibited by patients.

[TG Therapeutics, Inc.] TG Therapeutics, Inc. announced the US FDA has extended the Prescription Drug User Fee Act (PDUFA) goal date to June 25, 2022 for the Biologics License Application (BLA) and supplemental New Drug Application (sNDA) for ublituximab in combination with UKONIQ®as a treatment for patients with chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL).

[Seminars in Cell & Developmental Biology] Scientists review the role of mitochondrial apoptotic signaling in skeletal muscle remodeling during myogenic differentiation and skeletal muscle pathological states, including aging, disuse, and muscular dystrophy.