macrophages

[Nucleic Acids Research] Investigators reported that cold shock protein (CspC)—but not CspE—is necessary to activate the master virulence regulator PhoP when Salmonella enterica serovar Typhimurium experienced mildly acidic pH, such as inside macrophages.

[Cancer Research] Investigators showed that membranous HER3 protein was commonly highly expressed in lethal prostate cancer, associating with reduced time to castration resistance and survival.

[Cell Death Discovery] Bone marrow transplantation was performed from swiprosin-1-knockout mice and age-matched ApoE−/− mice. Atherosclerotic lesion, serum lipid, and interleukin-β levels were detected.

[ACS Nano] The authors developed a precise M2 TAM-targeted delivery system using “eat-me” and “don’t-eat-me” signals.

[Cell Death & Disease] Researchers used a model of cerebral contusion and receptor interacting protein kinase 3 (RIPK3) and mixed lineage kinase like knockout (MLKL−/−) mice, and found evidence for activation of RIPK3 and MLKL and assembly of a RIPK1-RIPK3-MLKL necrosome complex in pericontusional brain tissue.

[Stem Cell Research & Therapy] The authors showed that donor differences in human MSC (hMSC) transcriptome were minor relative to the intrinsic differences in tissue-of-origin. hMSCs with different transcriptomic profiles showed potential differences in functional characteristics.