Single-Cell RNA-Seq of Out-of-Thaw Mesenchymal Stromal Cells Shows Tissue-of-Origin Differences and Inter-Donor Cell-Cycle Variations

The authors showed that donor differences in human MSC (hMSC) transcriptome were minor relative to the intrinsic differences in tissue-of-origin. hMSCs with different transcriptomic profiles showed potential differences in functional characteristics.