macrophages

[Signal Transduction and Targeted Therapy] Macrophages are among the most abundant immune cells in colorectal cancer. Differentially expressed genes were found to be enriched in unfolded protein response/endoplasmic reticulum stress response processes, and XBP1 splicing/activation was specifically observed in tumor-associated macrophages.

[Molecular Therapy-Nucleic Acids] The authors reported DGUOK-AS1 overexpression promoted breast cancer cell migration, angiogenesis, and macrophage migration, mediated by the increased secretion of IL11, which was extremely important for cancer progression.

[Scientific Reports] Intraperitoneal injection of lipopolysaccharide and oral gavage of ampicillin increased IFN-γ and TNF-α expression in the spleen, colon, and hippocampus, while IL-10 expression decreased.

[Oncogene] To identify clinically relevant microenvironmental and cancer features, scientists applied single-cell RNA sequencing to ten human lung adenocarcinomas and ten normal control tissues.

[Circulation Research] Researchers assessed the role of cardiac immune cells in the early hypertrophy response to cardiac pressure overload-induced by transverse aortic constriction.

[Scientific Reports] Scientists worked with electrospun nanofiber scaffold named that was composed of polyvinyl alcohol/iota carrageenan and doped with partially reduced graphene oxide that was successfully synthesized for wound healing and skin repair.