mast cells

[Scientific Reports] Researchers elucidated the overall smoking-induced miRNA changes and those specific to chronic obstructive pulmonary disease (COPD).They investigated the downstream effects on regulatory gene expression and the correlation to cellular composition.

[Nanomedicine] Investigators explored the effect of small extracellular vesicles from induced pluripotent stem cell-derived MSCs on acute pain and investigated the underlying mechanisms.

[Oncogene] Researchers investigated the role of the NFE2L3 transcription factor in inflammation-induced colorectal cancer.

[Signal Transduction and Targeted Therapy] Scientists showed that SARS-CoV-2-triggered mast cells degranulation initiated alveolar epithelial inflammation and lung injury.

[iScience] The authors showed that cultured HSCs expressed mast cell-related genes including Cd244 and suggested CD244 was a potent marker to exclude non-functional HSCs after in vitro culture thereby useful to elucidate mechanism of functional decline of HSCs during ex vivo treatment.

[Scientific Reports] Scientists describe the establishment of primary cocultures of neoplastic mast cells from canine cutaneous mast cell tumors and cancer-associated fibroblasts.