melanocytes

[Scientific Reports] Scientists investigated the potential biomarkers of vitiligo by evaluating the disease activity and curative effect of autologous cultured pure melanocyte transplantation on patients.

[Stem Cell Research & Therapy] Scientists reported that both human amniotic stem cells and their conditional medium had a potent anti-hyperpigmentation in skin in vivo and in vitro.

[Science Translational Medicine] Scientists performed single-cell RNA sequencing on affected and unaffected skin from patients with vitiligo, as well as healthy controls, to define the role of each cell type in coordinating autoimmunity during disease progression.

[Science] Using a combination of a human PSC–derived cancer model along with zebrafish transgenesis, researchers demonstrated that the transforming ability of BRAFV600E along with additional mutations depended on the intrinsic transcriptional program present in the cell of origin.

[Nature Cell Biology] Researchers used a single-cell enrichment and RNA-sequencing pipeline to study human epidermal melanocytes directly from the skin, capturing transcriptomes across different anatomical sites, developmental age, sexes and multiple skin tones.

[Life Sciences] Scientists investigated the relationship between melanin production and lipofuscin synthesis in normal mouse melanoma cell line B16F1 cells and Tyrosinase gene knockout cells.