melanoma

[Natural Product Research] The effects of Larrea divaricata, polyphenols and quercetin-3-methyl ether were assessed on B16F10 melanoma cells by determining the proliferation, viability, apoptosis induction and the expression and phosphorylation of STAT3.

[Nature Machine Intelligence] Investigators discovered that patients with more clonally expanded T cells that exhibit better affinity against truncal rather than subclonal neoantigens had more favourable prognosis and treatment response to immunotherapy in melanoma and lung cancer.

[Oncology Reports] Researchers evaluated the role of the lncRNA TINCR ubiquitin domain containing TINCR in cutaneous malignant melanoma in vitro and in vivo.

[Environmental Science and Pollution Research] Researchers investigated the effects of polybrominated diphenyl ethers used as flame retardants on phenotypic features of melanoma cells that are important for cancer.

[Cancer Cell] Melanoma is a fatal skin malignant tumor with a poor prognosis, researchers found that lncRNA BASP1-AS1 was essential for the development and prognosis of melanoma.

[Bristol Myers Squibb] Bristol Myers Squibb announced that the US FDA has accepted for priority review the Biologics License Application for the LAG-3-blocking antibody relatlimab and nivolumab fixed-dose combination, administered as a single infusion, for the treatment of adult and pediatric patients with unresectable or metastatic melanoma.