mesenchymal cells

[International Journal of Oral Science] Investigators assessed the cell fate of PRX1+ cells during molar development and periodontal ligament (PDL) formation in mice, and performed single-cell RNA sequencing analysis to study the distribution of PRX1+ cells in PDL cells.

[Development] Scientists presented a light-sheet fluorescence microscopy approach to image the pancreas in 3D and map tissue interactions at key time points in the mouse embryo.

[Journal of Bioscience and Bioengineering] The authors demonstrated that electrical stimulation (ES) with a polypyrrole-modified electrode upregulated trichogenic gene expression in human dermal papilla cells in vitro, and the activated cells when transplanted into mice generated double the number of hairs compared to that without the ES.

[Cellular Signalling] Scientists analyzed Clinical Proteomic Tumor Analysis Consortium, colon tissue microarray, and colon cancer cells to evaluate the ESRP1 expression levels in colorectal cancer subtypes.

[Nature Cell Biology] Researchers demonstrated that human alveolar type 2 cells (hAEC2s), unlike murine AEC2s, transdifferentiated into basal cells in response to fibrotic signaling in the lung mesenchyme, in vitro and in vivo.

[Inflammatory Bowel Diseases] Induced pluripotent stem cells from two control individuals and two very early onset inflammatory bowel disease patients with structuring complications were obtained and directed to form human intestinal organoids.