mesenchymal markers

[Cell Death Discovery] Researchers determined the effect and potential mechanism of Heparanase on glomerular endothelial cells phenotype under high-glucose conditions.

[Journal of Mammary Gland Biology and Neoplasia] Investigators found that chronic leptin treatment induced a switch from an epithelial to a mesenchymal morphology, partial loss of E-cadherin and gain of vimentin expression.

[Scientific Reports] Scientists demonstrated for the first time that TGF-β could elicit epithelial–mesenchymal transition in a mouse lung adenocarcinoma cell line.

[Medical Oncology] Scientists reported that although silencing Akt1 enhanced the invasion of prostate cancer (PCa) cells induced by nutritional starvation (NST) in vitro, silencing Akt1 inhibited the PCa lung metastasis induced by NST in vivo.

[Cell Biology International] Scientists investigated the expression of N-Cadherin, a trans-membrane protein that enhanced the cell adhesion and recently gained attention for differentiation and augmentation of stem cell function, in mouse cardiac MSCs.

[JCI Insight] Researchers aimed to better understand the tumor epithelium-targeted mechanisms of bacterial cancer therapy by using autochthonous mouse models of intestinal cancer and tumor organoid cultures to assess the effectiveness and consequences of oral treatment with aromatase A-deficient STm.