Glycogen Synthase Kinase‐3β Promotes Radiation‐Induced Lung Fibrosis by Regulating β‐Catenin/lin28 Signaling Network to Determine Type II Alveolar Stem Cell Transdifferentiation State

Scientists explored the expressions of cell phenotype markers and differentiation regulators in isolated type II alveolar epithelial stem cells (AEC II) to analyze the correlation between GSK‐3β/TGF‐β1/β‐catenin signaling pathway, lin28/let‐7 balance, and AEC II phenotypes at different injury phases following irradiation.
[FASEB Journal]
Zhang, T., Zhou, J., Yue, H., Du, C., Xiao, Z., Zhao, W., Li, N., Wang, X., Liu, X., Li, Y., Geng, X., Zhang, Y., Li, L., & Tian, J. (n.d.). Glycogen synthase kinase-3β promotes radiation-induced lung fibrosis by regulating β-catenin/lin28 signaling network to determine type II alveolar stem cell transdifferentiation state. The FASEB Journal, n/a(n/a). https://doi.org/10.1096/fj.202001518 Cite
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