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mesenchymal stem cells

Intra-Articular Injection of miR-29a-3p of BMSCs Promotes Cartilage Self-Repairing and Alleviates Pain in the Rat Osteoarthritis

[Tissue Engineering and Regenerative Medicine] Scientists investigated the therapeutic efficacy of intra-articular injection of bone marrow mesenchymal stem cells transfected with miR-29a-3p inhibitor in osteoarthritis.

Dose-Dependent Effect of Mesenchymal Stromal Cells Co-Grafted with Dopaminergic Neurons in a Parkinson’s Disease Rat Model

[Journal of Cellular and Molecular Medicine] Researchers investigated whether co-grafting of MSCs could improve the survival and reinnervation ability of dopaminergic precursors transplanted in animal models of Parkinson's disease.

Mesenchymal Stem Cells Act as Stimulators of Neurogenesis and Synaptic Function in a Rat Model of Alzheimer’s Disease

[Heliyon] The possible roles of human umbilical mesenchymal stromal cord and adipose mesenchymal stem cells in neurogenesis and synaptic function were investigated using a β-amyloid 1-42-induced Alzheimer's disease rat model.

The Current Challenges on Spray-Based Cell Delivery to the Skin Wounds

[Tissue Engineering Part C-Methods] Keratinocytes, fibroblasts, melanocytes, and mesenchymal stem cells (MSCs) are promising cell sources for cell spray procedures. Scientists focus on the different types of cells and spray instruments used in cell delivery procedures.

Mesenchymal Stromal Cell-Secreted CCL2 Promotes Antibacterial Defense Mechanisms through Increased Antimicrobial Peptide Expression in Keratinocytes

[Stem Cells Translational Medicine] Scientists tested the efficacy of the MSC secretome in a physiologically relevant ex vivo equine skin biofilm explant model and explored the impact of the MSC secretome on the antimicrobial defense mechanisms of resident skin cells.

Biological Resurfacing in a Canine Model of Hip Osteoarthritis

[Science Advances] Scientists used 3D weaving, additive manufacturing, and autologous mesenchymal stem cells to create a tissue-engineered, bicomponent implant to restore hip function in a canine hip osteoarthritis model.

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