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mesenchymal stem cells

Mesenchymal Stem Cells: Ideal Seeds for Treating Diseases

[Human Cell] MSCs, a kind of multipotent stem cells with self-renewal ability and multi-differentiation ability, have become the “practical stem cells” for the treatment of diseases.

Brooklyn ImmunoTherapeutics Completes Acquisition of Novellus Therapeutics

[Brooklyn ImmunoTherapeutics, Inc.] Brooklyn ImmunoTherapeutics, Inc. has announced that it had completed its acquisition of Novellus Therapeutics Limited. Novellus is developing next‑generation engineered MSC therapies using extensively patented mRNA-based cell reprogramming and gene editing technologies.

A Comparative Study of Mesenchymal Stem Cell Transplantation and NTG-101 Molecular Therapy to Treat Degenerative Disc Disease

[Scientific Reports] Investigators compared the therapeutic potential of a novel drug candidate, NTG-101 to MSCs, including rat cartilage derived stem cells, bone marrow stem cells and human umbilical cord derived MSCs for the treatment of Degenerative Disc Disease.

Engineered Mucoperiosteal Scaffold for Cleft Palate Regeneration towards the Non-immunogenic Transplantation

[Scientific Reports] The authors set up a new natural scaffold deriving from a decellularized porcine mucoperiosteum, engineered by an innovative micro-perforation procedure based on Quantum Molecular Resonance and then subjected to in vitro recellularization with human bone marrow-derived mesenchymal stem cells.

Cell Therapy in Patients with COVID-19 Using Wharton’s Jelly Mesenchymal Stem Cells: A Phase I Clinical Trial

[Stem Cell Research & Therapy] Scientists assessed the safety and efficacy of injecting intravenous Wharton’s jelly-derived MSCs in patients with COVID-19 as a treatment. Five patients with severe COVID-19 were treated with Wharton’s jelly-derived mesenchymal stem cells.

Embelin Downregulated cFLIP in Breast Cancer Cell Lines Facilitate Anti-Tumor Effect of IL-1β-Stimulated Human Umbilical Cord Mesenchymal Stem Cells

[Scientific Reports] Scientists found that IL-1β-stimulated human umbilical cord-derived mesenchymal stem cells enhanced the expression of membrane-bound and soluble tumor necrosis factor-related apoptosis-inducing ligand.

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