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mesenchymal stem cells

Human Umbilical Cord Mesenchymal Stromal Cells Attenuate Pulmonary Fibrosis via Regulatory T Cell through Interaction with Macrophage

[Stem Cell Research & Therapy] The molecular and cellular behavior of human umbilical cord MSC was investigated in a bleomycin-induced mouse pulmonary fibrosis model.

Influence of the Mesenchymal Stromal Cell Source on the Hematopoietic Supportive Capacity of Umbilical Cord Blood-Derived CD34+-Enriched Cells

[Stem Cell Research & Therapy] The authors compared the capacity of BM-, umbilical cord matrix-, and adipose tissue-derived MSC, expanded with/without xenogeneic components, to expand/maintain umbilical cord blood CD34+-enriched cells ex vivo.

Human Umbilical Cord-Derived Mesenchymal Stem Cells Improve the Function of Liver in Rats with Acute-on-Chronic Liver Failure via Downregulating Notch and Stat1/Stat3 Signaling

[Stem Cell Research & Therapy] Researchers investigated the therapeutic potential of human umbilical cord-derived MSCs in acute-on-chronic liver injury (ACLI) and ACLF rat models.

Glycemic Control by Umbilical Cord-Derived Mesenchymal Stem Cells Promotes Effects of Fasting-Mimicking Diet on Type 2 Diabetic Mice

[Stem Cell Research & Therapy] The authors investigated the efficacy comparison and interaction between fasting-mimicking diet and umbilical cord-derived-MSC infusion, aiming to establish effective type 2 diabetes therapies and explore its mechanism.

Regional Specialization and Fate Specification of Bone Stromal Cells in Skeletal Development

[Cell Reports] Investigators showed with mouse genetics, ex vivo cell differentiation assays, and transcriptional profiling that mesenchymal stromal cells from bone from metaphysis and diaphysis were fundamentally distinct.

The Potential Role of Mesenchymal Stem Cells in Modulating Anti-Aging Process

[Cell Biology International] Investigators describe in detail ways MSCs may capitalize its paracrine properties in modulating antiaging process.

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