mesenchymal stem cells

[Stem Cell Research & Therapy] Researchers showed that c-Myc greatly improved the trans-differentiation efficiency for hepatoblast-like cells (HLCs) from human umbilical cord mesenchymal stem cells, which remained highly efficient in reprogramming fibroblasts into HLCs.

[Laboratory Investigation] The authors investigated the role of hypoxia/serum deprivation-induced M1-type macrophage-derived exosomes on bone marrow MSC viability, migration, and apoptosis.

[Scientific Reports] Scientists isolated and characterized adipose-derived MSCs from the visceral adipose tissue surrounding a pheochromocytoma, a model of inducible brown adipose tissue in humans.

[Science Advances] Scientists genetically engineered MSCs with Exendin-4, a glucagon-like peptide-1 analog, and demonstrated their boosted cellular functions and antidiabetic efficacy in a type 2 diabetes mellitus mouse model.

[Biological Chemistry] The authors address recent findings for enhanced epidermal-dermal regenerative processes on collagen/glycosaminoglyca(GAG)n-based matrices containing sulfated GAG in simple and complex in vitro models.

[Acta Biomaterialia] The authors synthesized a sodium alginate (SA)/collagen type I (Col)/stromal cell-derived factor-1 (SDF-1) hydrogel and investigated whether the SA/Col/SDF-1 hydrogel loaded with bone marrow-derived MSCs had therapeutic effects on a traumatic brain injury model.