Researchers showed that c-Myc greatly improved the trans-differentiation efficiency for hepatoblast-like cells (HLCs) from human umbilical cord mesenchymal stem cells, which remained highly efficient in reprogramming fibroblasts into HLCs.
[Stem Cell Research & Therapy]
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Deng, J., Luo, K., Xu, P., Jiang, Q., Wang, Y., Yao, Y., Chen, X., Cheng, F., Xie, D., & Deng, H. (2021). High-efficiency c-Myc-mediated induction of functional hepatoblasts from the human umbilical cord mesenchymal stem cells. Stem Cell Research & Therapy, 12(1), 375. https://doi.org/10.1186/s13287-021-02419-1 Cite