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mesenchymal stem cells
Cell Therapy News
Sciatic Nerve Regeneration After Traumatic Injury Using Magnetic Targeted Adipose-derived Mesenchymal Stem Cells
[Acta Biomaterialia] Adipose-derived mesenchymal stem cells were loaded with citric acid coated superparamagnetic iron oxide nanoparticles, systemically transplanted and magnetically recruited to the injured sciatic nerve.
Cell Therapy News
Human-Induced Neural and Mesenchymal Stem Cell Therapy Combined with a Curcumin Nanoconjugate as a Spinal Cord Injury Treatment
[International Journal of Molecular Sciences] Researchers report on the development of an enhanced synergistic combination therapy comprising polyacetal–curcumin nanoconjugate and neural stem cells derived from induced pluripotent stem cells + mesenchymal stem cells treatment as a treatment option for severe sub-acute traumatic spinal cord injury.
Umbilical & Placental Cell News
VEGF165 Gene-Modified Human Umbilical Cord Blood Mesenchymal Stem Cells Protect against Acute Liver Failure in Rats
[Journal of Gene Medicine] Human umbilical cord blood-MSCs were infected with the adenovirus expressing GFP-VEFG fusion protein to overexpress VEGF165 or the adenovirus expressing GFP as control.
Mesenchymal Cell News
A Novel Therapeutic Approach for Inflammatory Bowel Disease by Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells to Repair Intestinal Barrier via TSG-6
[Stem Cell Research & Therapy] Two separate dextran sulfate sodium and 2,4,6-trinitrobenzenesulfonic acid induced inflammatory bowel disease mouse models were intraperitoneally administered MSCs-Exo extracted from human umbilical cord MSC culture supernatant.
Umbilical & Placental Cell News
PRL-1 Overexpressed Placenta-Derived Mesenchymal Stem Cells Suppress Adipogenesis in Graves’ Ophthalmopathy through SREBP2/HMGCR Pathway
[Stem Cell Research & Therapy] Investigators constructed PRL-1 overexpressed human placental mesenchymal stem cells in an attempt to enhance the suppressive function of adipogenesis in Graves’ ophthalmopathy animal models.
Umbilical & Placental Cell News
Human Umbilical Cord Mesenchymal Stromal Cell Treatment of Severe COVID-19 Patients: A Three-Month Follow-Up Study Following Hospital Discharge
[Stem Cells and Development] In this three-month follow-up study, researchers examined discharged patients who had received human umbilical cord-MSC therapy to assess the safety of this therapy and the health-related quality of life of these patients.