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mesenchymal stem cells

Sciatic Nerve Regeneration After Traumatic Injury Using Magnetic Targeted Adipose-derived Mesenchymal Stem Cells

[Acta Biomaterialia] Adipose-derived mesenchymal stem cells were loaded with citric acid coated superparamagnetic iron oxide nanoparticles, systemically transplanted and magnetically recruited to the injured sciatic nerve.

Human-Induced Neural and Mesenchymal Stem Cell Therapy Combined with a Curcumin Nanoconjugate as a Spinal Cord Injury Treatment

[International Journal of Molecular Sciences] Researchers report on the development of an enhanced synergistic combination therapy comprising polyacetal–curcumin nanoconjugate and neural stem cells derived from induced pluripotent stem cells + mesenchymal stem cells treatment as a treatment option for severe sub-acute traumatic spinal cord injury.

VEGF165 Gene-Modified Human Umbilical Cord Blood Mesenchymal Stem Cells Protect against Acute Liver Failure in Rats

[Journal of Gene Medicine] Human umbilical cord blood-MSCs were infected with the adenovirus expressing GFP-VEFG fusion protein to overexpress VEGF165 or the adenovirus expressing GFP as control.

A Novel Therapeutic Approach for Inflammatory Bowel Disease by Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells to Repair Intestinal Barrier via TSG-6

[Stem Cell Research & Therapy] Two separate dextran sulfate sodium and 2,4,6-trinitrobenzenesulfonic acid induced inflammatory bowel disease mouse models were intraperitoneally administered MSCs-Exo extracted from human umbilical cord MSC culture supernatant.

PRL-1 Overexpressed Placenta-Derived Mesenchymal Stem Cells Suppress Adipogenesis in Graves’ Ophthalmopathy through SREBP2/HMGCR Pathway

[Stem Cell Research & Therapy] Investigators constructed PRL-1 overexpressed human placental mesenchymal stem cells in an attempt to enhance the suppressive function of adipogenesis in Graves’ ophthalmopathy animal models.

Human Umbilical Cord Mesenchymal Stromal Cell Treatment of Severe COVID-19 Patients: A Three-Month Follow-Up Study Following Hospital Discharge

[Stem Cells and Development] In this three-month follow-up study, researchers examined discharged patients who had received human umbilical cord-MSC therapy to assess the safety of this therapy and the health-related quality of life of these patients.

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