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monocytes

YAP1 Induces Marrow Derived Suppressor Cell Recruitment in Chlamydia trachomatis Infection

[Immunology Letters] Scientists explored the role of marrow derived suppressor cells in the immune escape mechanism of Chlamydia trachomatis.

Long-Term Recruitment of Endogenous M2 Macrophages by Platelet Lysate-Rich Plasma Macroporous Hydrogel Scaffold for Articular Cartilage Defect Repair

[Advanced Healthcare Materials] A platelet lysate-rich plasma macroporous hydrogel scaffold with around 100 μm pore size and 1.25 MPa Young's modulus was developed to sustainedly recruit and polarize endogenous anti-inflammatory macrophages for improving cartilage defect repair.

Systemic and Local Innate Immune Responses to Surgical Co-Transplantation of Mesenchymal Stromal Cells and Biphasic Calcium Phosphate for Bone Regeneration

[Acta Biomaterialia] Scientists assessed the local and systemic innate immune responses to implantation of biphasic calcium phosphate biomaterial alone, or with bone marrow derived MSC, in critical-sized calvarial bone defects of Lewis rats.

Therapeutic IGF-I Receptor Inhibition Alters Fibrocyte Immune Phenotype in Thyroid-Associated Ophthalmopathy

[Proceedings of the National Academy of Sciences of the United States of America] Investigators demonstrated that teprotumumab, an anti-insulin-like growth factor I receptor inhibitor, attenuated constitutive expression and induction by the thyroid-stimulating hormone of MHC II and these B7 members in CD34+ fibrocytes.

A Multivariate Modeling Framework to Quantify Immune Checkpoint Context-Dependent Stimulation on T Cells

[Cell Discovery] Researchers established an experimental system including a stimulus of interest, applied to an immune cell type in several contexts.

TMT-Based Quantitative Proteomic Profiling of Human Monocyte-Derived Macrophages and Foam Cells

[Proteome Science] Human peripheral blood mononuclear cells were stimulated with macrophage colony-stimulating factor, and obtained macrophages were transformed into foam cells by oxidized low-density lipoprotein.

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